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NEW QUESTION: 1
履歴追跡は、以下の標準オブジェクトで実行できます。ただし、該当する選択肢を選択してください。
A. リード
B. 機会
C. 予測
D. アカウント
E. 連絡先
Answer: C
NEW QUESTION: 2
Which of the following statements about static analysis are FALSE?
I. Static analysis can be used instead of dynamic testing.
II. Static analysis can uncover defects like security vulnerabilities.
III. Static analysis can be used to check conformance to specifications and standards.
IV. Static analysis typically defects failures prior to component testing.
A. II, III
B. I, IV
C. III, IV
D. I, II
Answer: D
NEW QUESTION: 3
CJ is a 69-year-old male with a history of diabetes, hypertension and hypercholesterolemia. His fasting lipid profile is TC 530 mg/dL; LDL-C 125; HDL-C 48 mg/dL; and TG 640 mg/dL. His A1c 8.1, calculate creatinine clearance is 65mls/hr, BP 135/80 mm Hg, HR 70 beats /min.
His current medications include metformin 1000mg po bid, lisinopril 20mg daily, sitagliptin 50mg bid and atorvastatin 40mg daily.
What is the best pharmacological agent to initiate on CJ?
A. Gemfibrozil 600mg twice daily
B. Fenofibrate 162mg daily
C. Niacin 500mg twice daily
D. Fish oil 500mg twice daily
E. Increase atorvastatin to 80mg
Answer: B
Explanation:
Explanation
It is reasonable to add triglyceride-lowering medications such as fibrates or niacin to prevent pancreatitis in those with triglyceride levels >500 mg/dL, which applies to this patient as his TG level is 640 mg/dL.
C is wrong because gemfibrozil should not be initiated in patients on statin therapy because of an increased risk for muscle symptoms and rhabdomyolysis. Fenofibrate may be considered concomitantly with a low- or moderate- intensity statin when triglycerides are above 500 mg/dL,2, however he is on a high intensity statin therapy. For niacin, the IR dose should start at 100 mg TID2 and niacin does not lower triglyceride levels as much as fibrate do.4 Fenofibrates are dose adjusted for renal function lower than 60 mL/min to 54 mg/mL, so this dose is appropriate for this patient because of his renal function being above 60 mL/min. The best option is fenofibrate 162 mg daily, but this needs to be monitored for any symptoms of muscle pain exhibited by the patient, especially as the patient is at a higher risk due to being a diabetic. Fish oil is not a first line agent to treat hypertriglyceridemia.
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